Head-to-Head Model Comparison

Mistral Medium 3.5 vs Claude Opus 5.5

Benchmarks, API Token Pricing, Context Window & Speed Comparison

Reviewed by the GetInfoUs research teamLast reviewed: October 2026Editorial policy
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Compare Mistral Medium 3.5 by Mistral AI against Claude Opus 5.5 by Anthropic across real-world coding, reasoning, token economics, and latency.

Head-to-Head Comparison

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Popular Matchups:
Mistral AI

Mistral Medium 3.5

Enterprise Balanced

Frontier enterprise generalist offering 262K context, multimodal vision, hybrid reasoning, and open weights under attractive $0.40/$2.00 pricing.

Intelligence Index55 / 100
Input Token:

$0.40 / 1M

Output Token:

$2.00 / 1M

Context Window:

262.1K tokens

SWE-bench Verified:

54%

Anthropic

Claude Opus 5.5

Frontier Intelligence Titan

Anthropic's most intelligent model for complex reasoning, research, and strategic analysis.

Intelligence Index94 / 100
Input Token:

$4.00 / 1M

Output Token:

$20.00 / 1M

Context Window:

1M tokens

SWE-bench Verified:

84.6%

Key Differences at a Glance

  • Mistral Medium 3.5 is 9.6x cheaper for API usage (input + output tokens combined).
  • Claude Opus 5.5 has a larger context window (1M vs 262K tokens).
  • Mistral Medium 3.5 is faster at 90 tok/s vs 78 tok/s.
  • Claude Opus 5.5 leads on SWE-bench coding (84.6% vs 54.0%).
Need definitions for token pricing, context, or benchmarks?Explore AI Glossary →
FeatureMistral Medium 3.5Claude Opus 5.5
Intelligence Index
Composite reasoning & knowledge score (0-100)
5594
Provider
Mistral AIAnthropic
Input Price
Cost per million input tokens
$0.40 / 1M$4.00 / 1M
Output Price
Cost per million output tokens
$2.00 / 1M$20.00 / 1M
Blended Price
Weighted 7:2:1 cache:input:output per 1M
$0.35 / 1M$3.08 / 1M
Context Window
Maximum input + output tokens
262.1K tokens~393 A4 pages of text1M tokens~1,500 A4 pages of text
Max Output Tokens
Per single request
33K128K
Throughput Speed
Tokens generated per second
90 tok/s78 tok/s
SWE-bench Verified
Real-world software engineering
54%84.6%
GPQA Diamond
Graduate-level reasoning
68%82.3%
Cached Input Price
Prompt caching discount per 1M tokens
$0.10 / 1M$0.40 / 1M

Who Wins Where?

At-a-glance decision framework
Coding
Claude Opus 5.5
+30.6% SWE-bench lead
Cost
Mistral Medium 3.5
9.6x cheaper monthly runtime
Speed
Mistral Medium 3.5
+15% faster generation
Context
Claude Opus 5.5
1M tokens window

Empirical Head-to-Head Benchmark Scores

Official evaluation metrics verified by independent third-party research labs.

Mistral Medium 3.5Claude Opus 5.5
SWE-bench Verified (Autonomous Coding)

Industry benchmark evaluating real-world GitHub issue resolution and multi-file debugging.

54%vs84.6%
GPQA Diamond (Doctorate-Level Science & Math)

Challenging questions created by domain experts to test complex PhD-level reasoning.

68%vs82.3%
MMLU-Pro (Multi-task Language Understanding)

Hardened reasoning and academic knowledge benchmark with reduced lucky-guess probability.

84.5%vs91.5%
LMSYS Chatbot Arena Elo

Crowdsourced human preference evaluation based on blind, head-to-head model battles.

1370ptsvs1507pts
Humanity's Last Exam (Frontier Expert Knowledge)

Extremely difficult, closed-ended questions spanning the frontier of human expert knowledge.

N/Avs19.8%
Terminal-Bench (Agentic Coding & Terminal Use)

Autonomous multi-step tasks executed inside a real command-line terminal environment.

46%vs66.4%
SciCode (Scientific Computing)

Research-grade coding problems drawn from real scientific and numerical workloads.

N/Avs58.7%
LiveCodeBench (Competitive Coding)

Contamination-free competitive programming problems collected continuously over time.

N/Avs83.1%
AIME (Advanced Math Competition)

American Invitational Mathematics Examination — multi-step Olympiad-level reasoning.

78%vs95.4%
Long-Context Reasoning

Accuracy when reasoning over very large inputs that fill the model context window.

85%vs92.6%
Generation Speed (Throughput)

Tokens emitted per second during active generation streaming.

90 tok/s vs78 tok/s

Latency & Response Time

Time to first token (TTFT) and estimated end-to-end response time for a typical 500-token response.

Time to First Token (TTFT)Lower is better
Mistral Medium 3.50.45s
Claude Opus 5.51.40s
Est. End-to-End Response (500 tokens)TTFT + generation time
Mistral Medium 3.56.01s
Claude Opus 5.57.81s

Real-Time Interactive Token Cost Simulator

Adjust sliders to calculate projected monthly cloud API spending with prompt caching discounts.

100K / day
10K500K1M
30K / day
5K150K300K
50% cached
0% (Cold)50%90% (Warm)
Mistral Medium 3.5 Monthly API Bill
$2.55 / month
$0.4/1M in · $2/1M out
Claude Opus 5.5 Monthly API Bill
$24.60 / month
$4/1M in · $20/1M out
Mistral Medium 3.5 saves approximately $22.05 / month (90%) under this workload.9.6x Savings

Mistral Medium 3.5 · Strengths & Key Advantages

  • Expansive 262K context capacity with near-zero needle retrieval degradation
  • Highly attractive $0.40 in / $2.00 out pricing for an enterprise flagship
  • Open-weights availability with native visual and reasoning depth
Considerations & Trade-offs
  • Trails proprietary multi-trillion parameter giants on bleeding-edge coding
  • Requires dedicated enterprise hardware for full local deployment

Claude Opus 5.5 · Strengths & Key Advantages

  • Unmatched autonomous multi-step agentic coding and refactoring
  • Flawless multi-document reasoning over 1M token context with no long-prompt surcharge
  • Highest composite Intelligence Index score measured (94/100), leading SWE-bench Verified at 84.6%
  • Precise tool execution with robust error-recovery loops
Considerations & Trade-offs
  • Premium output pricing ($20.00/M) plus heavy reasoning-token usage (~68K output tokens per complex task) keeps long agentic runs expensive
  • Long thinking times at maximum effort can push a single hard agentic task toward ~$3.85+

Token Use & Task Economics

Estimated cost and token consumption to complete one representative agentic task.

MetricMistral Medium 3.5Claude Opus 5.5
Cost per Task
Estimated USD to finish one task
$0.38$3.85
Output Tokens / Task
Tokens generated per task
38K68K
Reasoning Tokens / Task
Thinking tokens burned per task
18K42K

Technical Specifications

Architecture, release timeline, capabilities, and modalities.

FeatureMistral Medium 3.5Claude Opus 5.5
Official API Model ID (SDK)mistral-medium-3-5-latestclaude-opus-5-5-20260901
API ProtocolOpenAI-Compatible REST / vLLM / SGLang / HuggingFace TGIAnthropic Messages API + AWS Bedrock + Vertex AI
Release Date2026-042026-09
Knowledge CutoffFebruary 2026June 2026
ArchitectureEnterprise Hybrid Reasoning MoEExtended Autonomous Hybrid Reasoning Transformer
ParametersConfidential (~80B MoE)Confidential
Enterprise Rate Limits (RPM / TPM)Unlimited (Hardware-bound on self-hosted GPU) / 10,000 RPM Cloud · Unlimited local throughput / 10M+ TPM Managed Cloud4,000 – 10,000 RPM (Tier 4 + Priority Tier) · 4,000,000 – 10,000,000 TPM
Long-Context Tier (>128K/200K)Flat rate ($0.4/1M in) across full 262K windowStandard rate up to 200K tokens; 2x input/output tier above 200K tokens
Prompt Cache Policy & TTLCached input at $0.1/1M tokens$0.4/1M cached read (90% off); 5-min default & 1-hour extended TTL
Computer Use / GUI AgentAPI / CLI Tool-Use & DOM Agent ready (no raw pixel desktop click loop)Supported (Screen coordinate grounding, browser & desktop GUI action loops)
MCP & Parallel Tool CallingNative MCP Client/Server ready · Parallel function calling · 100% Strict JSON SchemaNative MCP Client/Server ready · Parallel function calling · 100% Strict JSON Schema
Web Search Grounding & SandboxSupported via external Tavily/Exa Search & E2B/Docker Sandbox toolsNative Web Search Citations + Code Execution Tool + MCP Connectors
Official Fine-Tuning SupportFull Weights SFT, LoRA, QLoRA, DPO & GRPO RL (Unsloth / Axolotl / Llama-Factory)Custom Model Tuning via Amazon Bedrock & Prompt Distillation
Multimodal Token BillingText BPE (~4 chars/token) · Vision (~258–765 tokens per image tile)Text BPE (~4 chars/token) · Vision (~258–765 tokens per image tile)
Quantization & Min GPU VRAMBF16 / FP16, FP8 Dynamic, INT4 AWQ / GPTQ, GGUF (Q4_K_M / Q8_0) · 50 GB VRAM (4-bit Quantized) · 172 GB VRAM (Native BF16)Cloud-Hosted Proprietary (FP8 / BF16 Tensor Core Cluster) · Zero Local VRAM Required (100% Serverless Cloud API)
Safety & Frontier ClassificationOpen-Weights System Card + Customizable Guardrail Layer (Llama Guard / ShieldGemma)Anthropic RSP ASL-2 / ASL-3 Constitutional Safety Evaluated
Enterprise Compliance (ZDR/HIPAA/SOC2)100% Air-Gapped On-Premises / Private VPC · Full HIPAA, GDPR & SOC2 ControlSOC2 Type II · GDPR · Zero Data Retention (ZDR) & HIPAA BAA Available on Enterprise Tier
Input Modalitiestext, visiontext, vision
Output Modalitiestexttext

Mistral Medium 3.5 vs Claude Opus 5.5: Quick Answers

Which is more intelligent, Mistral Medium 3.5 or Claude Opus 5.5?

Claude Opus 5.5 is more intelligent. It scores 94 compared with 55 on the composite Intelligence Index.

Which model is faster?

Mistral Medium 3.5 is faster, generating 90 tokens per second compared with 78 tokens per second.

Which model is cheaper to run?

Mistral Medium 3.5 is cheaper at $0.35 per 1M tokens blended, compared with $3.08 (7:2:1 cache:input:output ratio).

Which model has lower latency?

Mistral Medium 3.5 has lower latency, with a time to first token of 0.45s compared with 1.40s.

Which model has a larger context window?

Claude Opus 5.5 has a larger context window, supporting 1M tokens compared with 262.1K tokens.

Verdict

Choose Mistral Medium 3.5 for enterprise intelligence hubs, sovereign multilingual workflows, and multi-turn analytical agents, or choose Claude Opus 5.5 for large-scale software development agents, enterprise codebases, and mission-critical scientific synthesis.

Frequently asked questions

Which is cheaper: Mistral Medium 3.5 or Claude Opus 5.5?+

Mistral Medium 3.5 costs $0.4/1M input and $2/1M output tokens, while Claude Opus 5.5 costs $4/1M input and $20/1M output tokens.

Which model has a larger context window: Mistral Medium 3.5 or Claude Opus 5.5?+

Mistral Medium 3.5 supports 262K tokens whereas Claude Opus 5.5 supports 1M tokens.

AI Terminology & Guide
Explore Glossary →

Understand key metrics like context window, token pricing, reasoning mode, and SWE-bench scores in our comprehensive AI glossary.

Benchmark scores, token prices, and rate limits evolve rapidly as AI labs release model updates. Always verify current specifications and pricing on the official provider documentation.

Sources: Mistral AI & Anthropic Official Documentation